Recruit a Patient
In recent developments, a 41 gene panel that allows for the screening of all the known genetic obesity syndromes has been approved by the UK Genetic Testing Network and is available to NHS patients from 1st April 2018.
Testing using the “Genetic Obesity Syndrome Panel” will be performed by the NHS Genetics Lab based at Addenbrooke’s Hospital, Cambridge, so please now send patient DNA through this route. Please download a copy of the request form to be used here.
This is a timely development as the Clinical Guidelines for the management of childhood obesity now recommend genetic testing as part of the assessment of children with severe obesity.
If you subsequently wish to recruit the patient into GOOS (ie: if the test is negative), the request card includes all the information we need so you will simply need to consent the patient/family and we will take care of the rest.
Of note, we no longer need to obtain plasma and serum/arrange couriers. We will screen for the relevant disorders, leptin deficiency and PCSK1 deficiency, as part of the genetic test.
Referrers from outside the UK
We are always happy to receive new referrals to the Genetics of Obesity Study (GOOS). We require some clinical and anthropometric information and blood samples for measurement of leptin, insulin and for DNA extraction.
The entry criteria for our study are:
Severe obesity (BMI > 3SD above the mean) of early onset (before age 10 years).
If you have any questions about the suitability of a patient, which samples to send, how to send them or any other questions, please contact us
Download the “GOOS information pack” for all the information necessary for you to refer a patient
We also have an information leaflet for healthcare professionals. Download it here.