Recruit a Patient
In recent developments, a 41 gene panel that allows for the screening of all the known genetic obesity syndromes has been approved by the UK Genetic Testing Network and is available to NHS patients.
Testing using the “Genetic Obesity Syndrome Panel” will be performed by the NHS Genetics Lab based at Addenbrooke’s Hospital, Cambridge, so please now send patient DNA through this route.
|Genetic Obesity Syndrome Panel request card (pdf)|
This is a timely development as the Clinical Guidelines for the management of childhood obesity now recommend genetic testing as part of the assessment of children with severe obesity.
|Clinical Guidelines for the management of childhood obesity (pdf)|
Due to the availability of the “Genetic Obesity Syndrome Panel” we will no longer be accepting new referrals to the Genetics of Obesity Study from UK referrers.
Referrers from outside the UK
We are always happy to receive new referrals to the Genetics of Obesity Study (GOOS). We require some clinical and anthropometric information and blood samples from the patient, affected siblings and parents for DNA extraction. In addition the patient should also be consented for whole exome sequencing to allow us to move quickly to exome sequencing if your patient does not have a mutation identified in a known obesity gene.
The entry criteria for our study are:
Severe obesity (BMI > 3SD above the mean) of early onset (before age 10 years).
If you have any questions about the suitability of a patient, which samples to send, how to send them or any other questions, please contact us
|GOOS clinical questionnaire|
|Whole exome sequencing consent form|
|Whole exome sequencing information sheet|